新生儿是比较特殊的一段时期,可以从食物中完整地吸收一些蛋白质。但
是实验表明,即使用药理学浓度的IGF-1喂养新生儿,也不能使血液中IGF-1的
浓度发生变化,用同位素标记法直接测量发现,从新生儿肠道吸收的IGF-1的
量可以忽略(Donovan and Odle, 1994; Odle et al., 1996; Burrin, 1997;
Burrin et al, 1997;Donovan et al, 1997)。
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Donovan SM et al (1997) Orally administered iodinated recombinant human insulin-like growth factor-I (IGF-1) is poorly absorbed by the neonatal piglet. J. Pediatr. Gastroenterol. Nutr. 24, 174-182
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Renehan AG et al (2004) Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis. Lancet 363, 1346–1353. 作者: chuanchuan 时间: 2008-9-17 17:42